Results 131 to 140 of about 874,910 (336)

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Weak grip strength predicts higher unplanned healthcare utilization among patients with heart failure

ESC Heart Failure
Aims Frailty increases healthcare utilization and costs for patients with heart failure but is challenging to assess in clinical settings. Hand grip strength (GS) is a single‐item measure of frailty yet lacks evidence as a potential screening tool to ...
Louisa Camille Poco, Eric Finkelstein, David Sim, Chetna Malhotra   +3 more
doaj   +1 more source

Fully integrated wearable sensor arrays for multiplexed in situ perspiration analysis

Nature, 2016
Wei Gao, S. Emaminejad, H. Nyein, Samyuktha Challa, Kevin Chen, Austin J Peck, H. Fahad, H. Ota, Hiroshi Shiraki, D. Kiriya, D. Lien, G. Brooks, Ronald W. Davis, A. Javey   +13 more
semanticscholar   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Quality of life and its predictors among patients with metastatic cancer in Bangladesh: the APPROACH survey

BMC Palliative Care
Background This study aimed to assess the health-related quality of life (HRQOL) (physical, functional, emotional, social, spiritual) and psychological (anxiety and depression) well-being and their associations with patient characteristics among patients
Rubayat Rahman, Lubna Mariam, Rebecca Su, Chetna Malhotra, Semra Ozdemir   +4 more
doaj   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Un territoire d’attaches: lien aux lieux et lien aux autres dans le périurbain francilien

, 2016
Marianne Thébert, Monica Coralli, Hélène Nessi, P. Sajous   +3 more
semanticscholar   +1 more source

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Nature, 2010
P. Duewell, H. Kono, K. Rayner, C. Sirois, G. Vladimer, F. Bauernfeind, G. Abela, L. Franchi, G. Núñez, M. Schnurr, T. Espevik, E. Lien, K. Fitzgerald, K. Rock, K. Moore, S. Wright, V. Hornung, E. Latz   +17 more
semanticscholar   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Une analyse empirique du lien entre investissement public et privé

, 2015
J. Creel, P. Hubert, Francesco Saraceno
semanticscholar   +1 more source