Results 41 to 50 of about 874,910 (336)
Journal of Immunology, 1999 Invasive infection with Gram-positive and Gram-negative bacteria often results in septic shock and death. The basis for the earliest steps in innate immune response to Gram-positive bacterial infection is poorly understood.
A. Yoshimura +5 more
semanticscholar +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
, 2013 A partir d’une revue de la litterature academique, cet article opere un examen critique de la mobilisation du concept de resilience dans le domaine de l’adaptation au changement climatique dans les systemes urbains.
Béatrice Quenault
semanticscholar +1 more source
Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke
New England Journal of Medicine, 2019 Background The time to initiate intravenous thrombolysis for acute ischemic stroke is generally limited to within 4.5 hours after the onset of symptoms.
Henry Ma +44 more
semanticscholar +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Ariel - Volume 12 Number 1 [PDF]
, 1981 Executive Editors David G. Polin Larry H. Pastor Business Manager Alex Macones Jean Lien Editorial Page Editor Sam Markind Photography Editors Ken Yonemura Lois Leach Sports Editor Todd ...
Collins, Diedre +9 more
core +1 more source
Estimation of the electron beam-induced specimen heating and the emitted X-rays spatial resolution by Kossel microdiffraction in a scanning electron microscope [PDF]
, 2012 Lien vers la version éditeur: http://www.sciencedirect.com/science/article/pii/S0304399112000307A Kossel microdiffraction experimental setup has been developed inside a Scanning Electron Micro-scope for crystallographic orientation, strain and stress ...
BERVEILLER, Sophie +3 more
core +4 more sources
Liens négatifs, liens perdus, liens latents
Calenda, 2012 Les travaux sur les relations sociales se développent ces dernières années permettant d’éclairer un certain nombre de faits sociaux comme l’accès à l’emploi, l’appui sur des réseaux professionnels ou personnels, l’évolution des relations amicales, etc.
openaire +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source