Results 91 to 100 of about 321,803 (309)
La danse de salon ou danse sociale: un outil du travailleur social pour favoriser l’insertion sociale de la personne marginalisée sur l’espace public et/ou en institution [PDF]
, 2017 Ce travail de Bachelor a pour thématique la danse de salon en lien avec la marginalité. Le travailleur social en lien avec la population marginalisée peut-il inclure la danse de salon comme outil éducatif ?
Baumgartner, Marie Cécile, Paul, Simon
core
Advanced Science, EarlyView.Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai +15 more
wiley +1 more source
Advanced Science, EarlyView.We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang +10 more
wiley +1 more source
Calenda, 2015 La Fondation pour le lien social de la Croix-Rouge française organise le jeudi 1er octobre 2015 à la Cité Internationale Universitaire un colloque intitulé « Travail et lien social ». Travail et identité, mutations, ruptures professionnelles, souffrances, vulnérabilités, accompagnement, épanouissement… Telles sont les thématiques qui orienteront le ...
openaire +1 more source
Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
Advanced Science, EarlyView.Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen +4 more
wiley +1 more source
Proudhon: l'atelier, la maison et l'avenir de l'art [PDF]
, 2009 Considering social link within the workshop and the household, and their interference with art and esthetism.Le lien social vu à travers la conjonction des deux pôles fondamentaux de l'économie, le foyer et l'atelier; le rôle de l'art dans la dynamique ...
Pasteur, Sébastien
core +2 more sources
IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury
Advanced Science, EarlyView.IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang +18 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Cuproptosis, an emerging form of programmed cell death, is capable of inducing mitochondrial dysfunction. Moreover, the PI3K‐AKT‐mTOR signaling pathway contributes to tumor cell progression by reprogramming mitochondrial morphology and function.
Lei Wu +10 more
wiley +1 more source
Advanced Science, EarlyView.This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang +13 more
wiley +1 more source