Results 111 to 120 of about 321,803 (309)

L’école algérienne et la problématique de l’éducation à la citoyenneté

open access: yesRevue des Sciences Humaines, 2015
La notion moderne de citoyenneté est productrice de lien démocratique et, par voie de conséquence, de lien social et de lien humain par l’égalité devant laquelle elle tient tous les hommes, tous les citoyens sans distinction de sexe, de condition, de ...
Allaoua BENDIF
doaj  

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

open access: yesAdvanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao   +11 more
wiley   +1 more source

La Responsabilité Sociétale de L'entreprise et Les Réactions des Parties Prenantes : le Cas de L'opérateur Téléphonique Mtn et des Utilisateurs de Téléphonie Mobile au Bénin [PDF]

open access: yes, 2013
The purpose of this research is to understand the mechanisms by which the actions of corporate social responsibility can affect organizational commitment and organizational identification consumers.
Maxime Jean Claude Hounyovi
core  

DCAF13 Safeguards Hematopoietic Stem Cells via RRS1‐Regulated Ribosome Biogenesis

open access: yesAdvanced Science, EarlyView.
This study establishes DCAF13 as an essential regulator for hematopoietic stem cell (HSC) function. Its deletion in mice causes lethal pancytopenia and HSC depletion. Mechanistically, DCAF13 interacts with RRS1 and mediates its non‐degradative K27‐linked ubiquitination, thereby stabilizing RRS1 to maintain ribosome biogenesis and protein translation ...
Mengke Li   +25 more
wiley   +1 more source

Durabilité et lien social : transitions et transactions dans l’expérimentation

open access: yesSociologies, 2016
Starting from the opposition between a technical and economic versus an ecological and social view of sustainability, clearly illustrated by the issue of renewable energy systems, this paper examines energy transition processes from a transactional ...
Philippe Hamman
doaj  

Numérisation, lien social, lectures

open access: yesCalenda, 2004
Journées d'études, Rethymno (Crète), 4-5 juin ...
openaire   +1 more source

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

open access: yesAdvanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann   +15 more
wiley   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy