Results 241 to 250 of about 60,981 (267)

From the Challenge of Peace to the Gift of Peace: Reading the Consistent Ethic of Life as an Ethic of Peacemaking [PDF]

, 2008
Lysaught, M. Therese
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Associations between AHA's Life's Essential 8 and cognition in midlife and older adults. [PDF]

Alzheimers Dement
Master L, Shen Y, Allan AC, Beydoun MA, Zonderman AB, Evans MK, Buxton OM, Gamaldo AA.   +7 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Functional and Circulating Indicators of Endothelial Health and Their Associations With the American Heart Association's Life's Essential 8. [PDF]

Am J Lifestyle Med
Cirillo JR, Stopfer KT, DeCataldo MK, Marsland AL, Muldoon MF, Scudder MR, Gianaros PJ.   +6 more
europepmc   +1 more source

Study Outlines of Elizabeth Harrison's "Child Nature" [PDF]

, 1915
Sackett, L.W.
core   +1 more source

Life's Essential 8 and Poor Brain Health Outcomes in Middle-Aged Adults. [PDF]

Neurology
Clocchiatti-Tuozzo S, Rivier CA, Renedo D, Huo S, Hawkes MA, de Havenon A, Schwamm LH, Sheth KN, Gill TM, Falcone GJ.   +9 more
europepmc   +1 more source

Life's Essential 8 and Incident Heart Failure Among REGARDS Participants With and Without Diabetes. [PDF]

JACC Heart Fail
Khodneva Y, Cherrington AL, Arora P, Blair J, Safford MM, Reid RJ, Sterling MR, Nordberg M, Goyal P, Levitan EB.   +9 more
europepmc   +1 more source

Dose-response relationship between Life's Essential 8 score and COPD risk: the NHANES cohort study 2007-2018. [PDF]

Front Med (Lausanne)
Huang Q, Yuan Q, Li W, He X, He Q, Deng Z.   +5 more
europepmc   +1 more source