Results 101 to 110 of about 660,152 (266)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Democracy Begins with the Parent [PDF]

open access: yes, 1979
PDF pages:
Hamdorf, Kent G.
core  

Sociodemographic Determinants of Life's Simple 7: Implications for Achieving Cardiovascular Health and Health Equity Goals.

open access: yesEthnicity & Disease, 2020
Background Life's Simple 7 (LS7; nutrition, physical activity, cigarette use, body mass index, blood pressure, cholesterol, glucose) predicts cardiovascular health.
B. Egan   +6 more
semanticscholar   +1 more source

Assessing Cardiovascular Health Using Life's Simple 7 in a Chinese Population Undergoing Stroke Prevention

open access: yesChinese Medical Journal, 2015
The American Heart Association/American Stroke Association proposed a metric called Life's Simple 7 (LS7) to define cardiovascular health (CVH). The presence of a large number of ideal components of CVH is associated with lower cardiovascular disease and all-cause mortality.
Qiong Yang   +5 more
openaire   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Circe and the Poets: Theocritus IX. 35-36 [PDF]

open access: yes, 1987
published or submitted for ...
Parry, Hugh
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Stress Among Health Care Professionals - The Need for Resiliency [PDF]

open access: yes, 2011
Healthcare professionals are subjected to considerable levels of stress such as work overload, excessive working hours, sleep deprivation, repeated exposure to emotionally charged situations, dealing with difficult patients and conflicts with other ...
Kakunje, Anil
core   +1 more source

Life’s Simple 7 Cardiovascular Health Metrics and Progression of Coronary Artery Calcium in a Low-Risk Population: A Cohort Study

open access: yesArteriosclerosis, Thrombosis and Vascular Biology, 2019
Objective— We examined the association of cardiovascular health (CVH) metrics with the development and progression of coronary artery calcium (CAC) among apparently healthy adults.
Seolhye Kim   +10 more
semanticscholar   +1 more source

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