Results 211 to 220 of about 10,012,980 (241)

Behavioral and health-factor domains of Life's Essential 8 in advanced cardiovascular-kidney-metabolic syndrome among Korean adults: a nationally representative cross-sectional analysis. [PDF]

Front Endocrinol (Lausanne)
Lim JA, Han K, Yu SH, Park JH, Moon S, Lee CB, Hong S.   +6 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Home health aides' perspectives towards achieving cardiovascular health and life's essential 8: a qualitative study. [PDF]

BMC Public Health
Sterling M, Avgar A, Phillips E, Kuo EF, Hernandez MY, Ringel J, Taveras YH, Lee A, Wiggins F, Moise N, Dell N, Landis C, Peramsetty R, Dicpinigaitis M, Safford M.   +14 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Associations of Life's Essential 8 cardiovascular health score with prevalent microvascular complications stratified by sex and menopausal status in Chinese adults with type 2 diabetes: a cross-sectional study. [PDF]

BMJ Open Diabetes Res Care
Qiu L, Feng Y, Zhou Y, Chen X, Yu J, Li L, Chattopadhyay K, Xu M, Li J.   +8 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Association between Life's Essential 8 and hyperuricemia in the Chinese elderly. [PDF]

Asia Pac J Clin Nutr
Jiao Y, Wang L, Hong X, Li W, Jiang H, Jia X, Wang H, Zhang B, Wang Z, Ding G.   +9 more
europepmc   +1 more source

Substitutional value of METS-IR for biochemical components of life's essential 8 in predicting incident mild cognitive impairment: A longitudinal cohort study. [PDF]

Medicine (Baltimore)
Zhu X, Wang C, Cao Q, Xu Q, Guo X, Liu C.   +5 more
europepmc   +1 more source

Association of life's essential 8 with chronic respiratory disease mortality and lung health: a national cohort study. [PDF]

BMJ Open Respir Res
Wu Y, Feng Y, Dai Z, Li J, Zhu M, Chen H, Cao C, Xiong K.   +7 more
europepmc   +1 more source