Results 101 to 110 of about 10,182,689 (231)
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Therapeutic Area: ASCVD/CVD Risk Factors Background: The American Heart Association (AHA) recently updated its Life's Simple 7 (LS7) cardiovascular health metric to Life's Essential 8 (LE8) by including sleep health and recognition of psychosocial ...
Mathias Lalika, MD, MPH
doaj +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
simple-dmrg/simple-dmrg: Simple DMRG 1.0
<p>SIMPLE DMRG tutorial, created for the Trieste summer school on quantum spin liquids.</p ...
James R. Garrison +3 more
core +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Background: Healthcare disparities are a major public health concern. It is known that ethnicity and educational status independently predict health outcomes.
Oni, Ebenezer T +19 more
core +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Türk devlet geleneğinde önemli bir yere sahip olan arşivcilik Osmanlı Devlet'i için de ayrı bir öneme sahip olmuştur. Osmanlı arşivinin en önemli defter serilerinden biri olan nâme-i hümayunlar Osmanlı Devleti'ne bağlı, yarı bağımsız hükümdarlara ...
Yılmaz, Fatma, Kuzucu, Serhat
core
Life's Simple 7: Vital But Not Easy
Eduardo Sanchez
doaj +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source

