Results 131 to 140 of about 692,170 (234)

CORRELATION BETWEEN THE AMERICAN HEART ASSOCIATION LIFE'S SIMPLE 7 AND LIFE'S ESSENTIAL 8 SCORES IN A COHORT OF AFRICAN AMERICAN ADULTS

American Journal of Preventive Cardiology
Therapeutic Area: ASCVD/CVD Risk Factors Background: The American Heart Association (AHA) recently updated its Life's Simple 7 (LS7) cardiovascular health metric to Life's Essential 8 (LE8) by including sleep health and recognition of psychosocial ...
Mathias Lalika, MD, MPH
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Can dementia risk be reduced by following the American Heart Association's Life's Simple 7? A systematic review and dose-response meta-analysis

Ageing Research Reviews, 2022
Jing Wu, Ying Xiong, Xin Xia, N. Orsini, C. Qiu, M. Kivipelto, D. Rizzuto, Rui Wang   +7 more
semanticscholar   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Key Topics on End-of-Life Care for African Americans [PDF]

, 2006
Racial classifications of human populations are politically and socially determined. There is no biological or genetic basis for these racial classifications. Health behaviors may be influenced by culture and poverty.
Bernice Harper, Bethsheba Johnson, Camilla Hudson, Diane Deese, Fay Burrs, Gloria Ramsey, Gwendolyn London, Harold Freeman, Jeremiah Wright, Jr., Joseph Dancy, Jr., Karla Holloway, Kelvin Calloway, LaVera Crawley, Michelle Grant Ervin, Myra Christopher, Paul Smith, Pernessa Seele, Richard Payne, Robert Washington, Rosalyn Priester, Sharon R. Latson, Skaykh Ibrahim Abdul-Malik, William Johnson, Willie Davis   +23 more
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Life's Simple 7: Vital But Not Easy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Eduardo Sanchez
doaj   +1 more source

undercurrent by Rita Wong [PDF]

, 2016
Review of Rita Wong\u27s ...
Shepherd, Kelly
core   +1 more source