Results 51 to 60 of about 10,182,689 (231)

Abstract 15351: Association of Life’s Simple 7 and Non-Alcoholic Fatty Liver Disease: The Multi-Ethnic Study of Atherosclerosis

, 2016
The AHA defined life’s simple 7 (LS7) as a measure of Cardiovascular health (CVH). Non-alcoholic fatty liver disease (NAFLD) is considered a significant risk factor for increased CVD. We evaluated ..
Oni, Ebenezer T, Blumenthal, Roger S., Ogunmoroti, Oluseye, Budoff, Matthew J., Martin, Seth S., Cushman, Mary, Blaha, Michael J., Veledar, Emir, Blankstein, Ron, Joshi, Parag H., Allen, Norrina B., Nasir, Khurram   +11 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Adjusted Prevalence Ratios for Poor Levels of Life’s Simple 7 Components for Participants With Compared to those Without Depressive Symptoms^*.

, 2013
*Prevalence ratios are for having poor levels versus intermediate or ideal levels of Life’s Simple 7 components comparing those with versus those without depressive symptoms.
Karina W. Davidson (292453), Ian M. Kronish (292451), April P. Carson (292452), Paul Muntner (292454), Monika M. Safford (292455)   +4 more
core   +1 more source

Table_1_Association between Life’s simple 7 and rheumatoid arthritis in adult Americans: data from the National Health and nutrition examination survey.DOCX

, 2023
ObjectiveThe study aimed to investigate the relationship between Life’s Simple 7 (LS7) and the risk of rheumatoid arthritis (RA) in adult Americans.MethodsA total of 17,532 participants were included in this study.
Ning Sheng (692423), Zhou Xiang (3353276), Jie Wang (16762), Fei Xing (134861)   +3 more
core   +1 more source

Cardiovascular Health Status, Migraine Risk, and Mortality Outcomes in Migraine Individuals: Insights From NHANES

Brain and Behavior
Objectives The study analyzes the link between cardiovascular health, measured through the Life's Simple 7 (LS7) score, and the potential risk of migraines. Moreover, the research delves into the possibility that better cardiovascular health might lessen
Hongwei Liu, Wenzhi Niu, Gaiying Ma, Haixia Fan, Minheng Zhang, Yu Wang, Mingni Yang   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

A precision medicine approach to sex-based differences in ideal cardiovascular health

Scientific Reports, 2021
Cardiovascular disease risk factor profiles and health behaviors are known to differ between women and men. Sex-based differences in ideal cardiovascular health were examined in the My Research Legacy study, which collected cardiovascular health and ...
Jane A. Leopold, Elliott M. Antman
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Association between Life’s Simple 7 and Menopause in a Community-based Population

Journal of Medical Sciences
Background: In 2010, the American Heart Association defined a new concept of ideal cardiovascular health (CVH) called Life’s Simple 7, which comprises seven parts, including smoking status (nonsmoking), body mass index (BMI) (
Wen-Chung Lu, Yuan-Ping Chao, Yung-Wen Cheng, Zhe-Yu Yang, Jun-Wei Huang, Tao-Chun Peng   +5 more
doaj   +1 more source