Results 21 to 30 of about 7,127,804 (259)

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

The Standard Family Life Course: An Assessment of Variability in Life Course Pathways

, 2012
Despite dramatic changes in family life over the past several decades, survey data demonstrate that a ‘standard’ family life course remains a goal for the vast majority.
Elizabeth Thomson, Maria Winkler-Dworak, Winkler-Dvorak, Maria, Kennedy, Sheela, Sheela Kennedy, Thomson, Elizabeth,   +5 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

From bad to worse? Effects of multiple adverse life course transitions on mental health

, 2018
This paper examines whether the simultaneous occurrence of two or more adverse life course transitions has a stronger effect on mental health compared to the effects of the sum of each.
Mandemakers, J.J., Mandemakers, Jornt, Kalmijn, Matthijs, Mandemakers, J., Kalmijn, M.   +4 more
core   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

An integrated and collaborative approach to developing and scripting questionnaires for longitudinal cohort studies and surveys: experience in Life Study [PDF]

, 2017
Efficient development of questionnaires for longitudinal surveys and cohort studies as computer-assisted survey instruments usually entails close collaboration between scientific and fieldwork teams. We describe a system based on the use of a Structured
Elias, P, Dezateux, Carol, Gilby, Nicholas, Walton, Suzanne, Peskett, Duncan, Nicholas Gilby, Alexandrakis, Stelios, Peter Elias, Carol Dezateux, Firman, N, Duncan Peskett, Dezateux, C, Gilby, N, Elias, Peter, Stelios Alexandrakis, Nicola Firman, Gareth Williams, Alexandrakis, S, Williams, Gareth, Walton, S, Suzanne Walton, Williams, G, Peskett, D, Firman, Nicola   +23 more
core   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Conceptual and Methodological Framework for a Digital Identity and Life-Course Study [PDF]

, 2023
The Digital Identity and Life-Course Study (DIALCS) project seeks to set the conceptual, theoretical and methodological foundations for a longitudinal life-course study focused on perceptions of, attitudes to, and behaviours with digital identity ...
Zeng, Yongyu, Buil-Gil, David, Renwick, Robin, Lu, Yang, Limniou, Maria   +4 more
core