Results 31 to 40 of about 7,127,804 (259)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi +6 more
wiley +1 more source
Developmental and Life-Course Criminology
, 2019 This chapter provides a brief overview of developmental and life-course criminology. These approaches are concerned with the study of the development of offending over the course of one's life, from onset to persistence and, eventually, desistance ...
Kazemian, Lila +2 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Relative Time and Life Course Research
, 2022 Mainstream life course studies often draw on a conventional understanding of time as a unidirectional clock-based entity, which proceeds in a uniform and linear manner.
Sánchez-Mira, Núria +2 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Negotiating the Life Course, 2010
, 2019 Negotiating the Life Course is designed to study the changing life courses and decision-making processes of Australian men and women as the family and society move from male breadwinner orientation, in the direction of higher levels of gender equity ...
Deborah Mitchell +4 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Negotiating the Life Course, 1997
, 2019 Negotiating the Life Course is designed to study the changing life courses and decision-making processes of Australian men and women as the family and society move from male breadwinner orientation in the direction of higher levels of gender equity.
Mitchell, Deborah A. +3 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Life Course Cube: A Tool for Studying Lives
, 2018 This paper proposes a conceptualization of the life course as a set of behavioral processes characterized by interdependencies that cross time, life domains, and levels of analysis.
Huinink, Johannes +2 more
core +1 more source