Results 121 to 130 of about 12,547,222 (301)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
PROF. DR. NECATİ ÖNER'İN FELSEFE ANLAYIŞININ HAYAT KAVRAMI ÇERÇEVESİNDE BİR ANALİZİ
Felsefe Dünyası, 2010 Bu makale felsefenin fert ve toplum hayatı açısından işlevi, hayatı anlama ve anlamlandırma konusundaki katkıları, Prof. Dr. Necati ÖNER'in felsefi düşünceleri çerçevesinde ele alınmış, onun felsefeye bakışı, eserlerinde ortaya koyduğu temel fikirleri ...
Abdulkuddüs Bingöl
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
NİETZSCHE'DE BİLGİ-YAŞAM İLİŞKİSİ
Felsefe Dünyası, 2008 Ogün ÜREK, "NİETZSCHE'DE BİLGİ-YAŞAM İLİŞKİSİ", FELSEFE DÜNYASI DERGİSİ, SAYI ...
Ogün Ürek
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Proceedings of the X International Crane Conference : [21–27 August 2023, Tartu, Estonia]
, 2023 We warmly welcome you to Tartu for the X International Crane Conference, hosted by the Estonian University of Life Sciences and organised in cooperation with the European Crane Working Group and the International Crane Foundation.
Estonian University of Life Sciences
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