Results 51 to 60 of about 1,079,597 (317)

Sex-specific components of frailty in C57BL/6 mice. [PDF]

, 2019
Many age-related biochemical, physiological and behavioral changes are known to be sex-specific. However, how sex influences frailty status and mortality risk in frail rodents has yet to be established.
Baumann, Cory W., Kwak, Dongmin, Thompson, LaDora V.   +2 more
core   +1 more source

Aging Intensity for Step-Stress Accelerated Life Testing Experiments

Entropy
The aging intensity (AI), defined as the ratio of the instantaneous hazard rate and a baseline hazard rate, is a useful tool for the describing reliability properties of a random variable corresponding to a lifetime. In this work, the concept of AI is introduced in step-stress accelerated life testing (SSALT) experiments, providing new insights to the ...
Francesco Buono, Maria Kateri
openaire   +6 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Performance Degradation Prediction and Reliability Evaluation of Rubber Aging in Natural Environment Under Alternating Cyclic Thermal Load

IEEE Access, 2019
With a focus on predicting the degradation of rubber performance in the natural environment and evaluating its reliability, the distribution law of accelerated aging life is analyzed through the accelerated aging test of hot oxygen.
Qiaobin Liu, Wenku Shi, Kunhen Li, Zhiyong Chen, Helong Liu   +4 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Deleterious mutations show increasing negative effects with age in Drosophila melanogaster

BMC Biology, 2020
Background In order for aging to evolve in response to a declining strength of selection with age, a genetic architecture that allows for mutations with age-specific effects on organismal performance is required.
Martin I. Brengdahl, Christopher M. Kimber, Phoebe Elias, Josephine Thompson, Urban Friberg   +4 more
doaj   +1 more source

Durability testing at one atmosphere of advanced catalysts and catalyst supports for automotive gas turbine engine combustors, part 1 [PDF]

, 1977
The durability of catalysts and catalyst supports in a combustion environment was experimentally demonstrated. A test of 1000 hours duration was completed with two catalysts, using diesel fuel and operating at catalytically supported thermal combustion ...
Carrubba, R., Chang, M., Heck, R. M., Hess, H.   +3 more
core   +2 more sources

The Life Orientation Test: A Confirmatory Factor Analysis Across Three Age Groups [PDF]

Innovation in Aging, 2020
Abstract The Life Orientation Test (LOT; Scheier & Carver, 1985) was developed as a measure of dispositional optimism. Optimism has been linked to positive life outcomes and is associated with psychological (Carver & Gaines, 1987; Scheier & Carver, 1985) and physical (Scheier & Carver, 1987; Scheier et al.
Intrieri, Robert, Goodwin, Paige
openaire   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Effects of age and eccentricity on visual target detection [PDF]

, 2013
The aim of this study was to examine the effects of aging and target eccentricity on a visual search task comprising 30 images of everyday life projected into a hemisphere, realizing a ±90° visual field.
Aeschimann, A, Bieri, R, Gruber, N, Mosimann, UP, Müri, RM, Nef, T, Nyffeler, T, Urwyler, P, Zito, GA   +8 more
core   +1 more source