Results 81 to 90 of about 13,579,615 (311)

[Coalition for Aging LGBT Pamphlet]

Pamphlet from the Coalition for Aging LGBT Records (The Dallas Way)
Coalition for Aging LGBT
core   +1 more source

Effect of Healthy Lifestyle Educational Programs on Happiness and Life Satisfaction in the Elderly: A Randomized Controlled Trial Study

Sālmand, 2019
Objectives Like the global population, the Iranian population is aging rapidly. Measures should be taken to maintain aging population healthy and happy.
Mohammad Mohammadi Mehr, Fereshteh Zamani-Alavijeh, Akbar Hasanzadeh, Tayebeh Fasihi   +3 more
doaj  

Playfulness in middle- and older age: testing associations with life satisfaction, character strengths, and flourishing

Aging & Mental Health
Objectives: Playfulness describes individual differences in (re)framing situations in a way that they are experienced as interesting, intellectually stimulating, or entertaining. We extended the study of playfulness to groups of middle- and higher age and examined the relations of four facets of playful- ness (Other-directed, Lighthearted, Intellectual,
Kay Brauer, Hannah Sophie Charlott Stumpf, René T. Proyer   +2 more
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Other title: Kansas State Advisory Council on Aging report for fiscal years--Other title: Kansas Advisory Council on Aging annual report

, 1979
The reports were prepared with the assistance of the Kansas Department on Aging.; Created in 1977 by the Kansas Act on the Aging, the ACA is represents different geographical, social and ethnic groups, with at least half its members being 60 years of age
Kansas Advisory Council on Aging.
core  

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Deciphering the timing and impact of life-extending interventions: temporal efficacy profiler distinguishes early, midlife, and senescence phase efficacies

Nature Communications
A growing number of compounds are reported to extend lifespan, but it remains unclear whether they reduce mortality across the entire life course or only at specific ages.
Nisi Jiang, Catherine J. Cheng, Qianqian Liu, Randy Strong, Jonathan Gelfond, James F. Nelson   +5 more
doaj   +1 more source

THE PROTHROMBIN TEST AND PIVKA-II IN BREASTFEDINFANTS AGED THE FIRST 6 MONTHS OF LIFE

Neonatology, surgery and perinatal medicine, 2017
Метою нашого дослідження було вивчення вітамін-К-залежних показників протромбінового комплексу гемостазу і змісту субстанції PIVKA-II, як маркера дефіциту вітаміну К, у дітей, які отримують грудне вигодовування від народження до 6 місяців життя.Матеріали та методи.
Ivanko, O. G., Solianik, O. V.
openaire   +3 more sources