Results 91 to 100 of about 2,952,860 (261)

Ontogeny influences sensitivity to climate change stressors in an endangered fish. [PDF]

open access: yes, 2014
Coastal ecosystems are among the most human-impacted habitats globally, and their management is often critically linked to recovery of declining native species.
Castillo, G   +6 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Adaptando mi vida: vivencias de cuidadores familiares de personas con enfermedad de Alzheimer

open access: yesGerokomos
RESUMEN La enfermedad de Alzheimer (EA) es una de las demencias más comunes y afecta al 8% de la población mayor de 65 años y al 30% de la población mayor de 80 años en los países con una alta expectativa de vida. Esta enfermedad es devastadora tanto por
Miriam Rubio Acuña   +3 more
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Reflections on Retirement: The Sunset Can be Spooktacular!

open access: yesPhilippine Journal of Otolaryngology Head and Neck Surgery
Where are we headed, oh, where have we gone? We’ve come a long way, now, let us move on. Dreams are for dreaming, wake up and they run, Life is for living, come, let us move on.1 1JF Lapena, Moving on   Retirement (n.);  from French ...
José Florencio Lapeña
doaj  

The Role of Life History Questionnaires in Defining Individualised Goals of Care for Clinical Cognitive Motor Dissociation Patients: A Pilot Study

open access: yesBrain Sciences
Background/Objectives: The aim of this pilot study is to qualitatively describe the use of life history questionnaires in an acute neurorehabilitation setting to define individualised goals of care for patients with clinical cognitive motor dissociation ...
Yago Rodriguez Mateos   +5 more
doaj   +1 more source

Developing an Agenda for Change for New Jersey's Urban Water Infrastructure [PDF]

open access: yes, 2014
A water infrastructure crisis looms in New Jersey's oldest and largest cities -- cities that comprise nearly one-fifth of the state's population and are projected to absorb much of its future growth, and yet have combined sewer systems, which carry both ...

core  

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Features of psychoemotional state of patients with psoriatic disease and overweight

open access: yesZaporožskij Medicinskij Žurnal, 2015
Data on the important role of stress in the etiology and pathogenesis of psoriatic disease necessitate research on the state of patients with psycho-emotional sphere. Aim.
V. O. Kiriyenko
doaj   +1 more source

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