Results 71 to 80 of about 1,010,607 (269)

Reflections on Retirement: The Sunset Can be Spooktacular!

Philippine Journal of Otolaryngology Head and Neck Surgery
Where are we headed, oh, where have we gone? We’ve come a long way, now, let us move on. Dreams are for dreaming, wake up and they run, Life is for living, come, let us move on.1 1JF Lapena, Moving on   Retirement (n.);  from French ...
José Florencio Lapeña
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Histórias de perdas fetais contadas por mulheres: estudo de análise qualitativa

Revista de Saúde Pública
OBJETIVO: (Re)conhecer o significado da perda fetal para mulheres que vivenciaram a experiência, a partir da compreensão do processo de gravidez, com base em seus relatos.
Alba Lúcia Dias dos Santos, Cornélio Pedroso Rosenburg, Keiko Ogura Buralli   +2 more
doaj  

A novel application of lemmatize and thematic analysis to understand protective measures perspectives of patients with chronic respiratory disease during the first outbreak of COVID-19 pandemic: a qualitative study

Frontiers in Public Health
ObjectiveTo describe the perspectives of a group of COPD patients during the first outbreak of the COVID-19 pandemic and narrate the emotions and polarity (acceptance-rejection) regarding living with COPD during the pandemic.Design/methodsWe used a novel
Domingo Palacios-Ceña, David Peña-Otero, David Peña-Otero, Ciro Casanova-Macario, Juan Nicolas Cuenca-Zaldivar, Juan Nicolas Cuenca-Zaldivar, Cristina Garcia-Bravo, Cesar Fernandez-de-las-Peñas, David Díaz-Pérez   +8 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Experiencing Breast Cancer Confronts Death but Reconciles with Life: A Qualitative Study Using Grounded Theory Methodology

Iatreia
Introduction: Breast cancer is the most common oncological diagnosis in women, and experiencing it generates physical, psychological, and social demands.
Ríos-Córdoba, Diana Carolina, Figueroa-Cuesta, Juan David, Alzate-Vanegas, Sandra Isabel, Contreras-Pérez, Daniel Fernando, Yepes-Delgado, Carlos Enrique   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

The Moderating Role of Emotional Intelligence on the Relationship Between Nurses’ Preparedness to Care for COVID-19 Patients and Their Quality of Work Life

Behavioral Sciences
Emotional intelligence (EI) is increasingly recognized as a key factor in healthcare, where managing emotions is vital for job satisfaction, productivity, and interpersonal relationships.
Hanan A. Alkorashy, Aisha F. Basheer, Hanem F. Mohamed   +2 more
doaj   +1 more source