Results 221 to 230 of about 9,912,419 (304)

The Digital Exposome: A Life Course Framework for Health in the Digital Age. [PDF]

J Med Internet Res
Petit P, Vuillerme N.
europepmc   +1 more source

Course, Life

, 2016
Course, Life
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Obesity and cryptorchidism across development: an integrated endocrine and metabolic life course framework. [PDF]

Front Endocrinol (Lausanne)
Zhang D, Li Q, Yang Z, Nong R, Zhanghuang C, Yan B.   +5 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Gaps in Population Life Course Phenotype Trajectories Underlying Major Noncommunicable Diseases: A Scoping Review. [PDF]

Int J Popul Data Sci
McBain K, Kasjan S, Taylor R, Dumuid D, Clifford S, Olds T, Wake M.   +6 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Lung function across the life course in Kenya: a series of cross-sectional surveys. [PDF]

ERJ Open Res
Meme H, Matu S, Orina F, Miheso B, Kiplimo R, Ndombi A, Kathure I, Kinyanjui J, Amukoye E, Chakaya J, He N, Bowyer C, Gray CM, Lesosky M, Mortimer K, Semple S, West SE, Zurba L, Binegdie AB, El Sony A, Devereux G.   +20 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Understanding the Rising Incidence of Early-Onset Colorectal Cancer: Life-Course Determinants and Opportunities for Primary Prevention. [PDF]

Cancers (Basel)
Alegre-Martinez A, Cabañas-Alite L, Fernández-Benet IE, Sánchez-Casalongue M, Martin-Moreno JM.   +4 more
europepmc   +1 more source