Results 21 to 30 of about 1,448,837 (262)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Instructive roles and supportive relationships: client perspectives of their engagement with community health workers in a rural south African home visiting program

International Journal for Equity in Health, 2021
Background Community health worker (CHW) programs have been positioned as a way to meet the needs of those who experience marginalization and inequitable access to health care, and current global health narratives also emphasize their adaptable nature to
Christina A. Laurenzi, Sarah Skeen, Bronwynè J. Coetzee, Vuyolwethu Notholi, Sarah Gordon, Emma Chademana, Julia Bishop, Mark Tomlinson   +7 more
doaj   +1 more source

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks, Molly Sonenklar, Cerelia Donald, Cecelia Valrie, Wally Smith, India Sisler   +5 more
wiley   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Long‐Term Course of Depression After Stroke and Risk Factors for Symptoms With Poor Progression: A Population‐Based Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Data on the long‐term poststroke depression trajectories and their determinants are limited. This study aims to estimate the 5‐year course of poststroke depression and identify risk factors for recurrent and persistent depression. Methods Data
Lu Liu, Iain J. Marshall, Ajay Bhalla, Xianqi Li, Salma Ayis, Charles D. A. Wolfe, Yanzhong Wang, Matthew D. L. O'Connell   +7 more
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

Long‐Term Risk of Stroke Recurrence: A  Competing Risk Analysis Based on the South London Stroke Register

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Previous studies on stroke recurrence often ignored the competing risk of death, potentially biasing risk estimates. This study estimated stroke recurrence risk and identified associated factors among patients with first‐ever stroke in South ...
Li Zhang, Marc Delord, Iain Marshall, Charles Wolfe, Yanzhong Wang, Matthew D. L. O’Connell   +5 more
doaj   +1 more source

Clinicians’ experiences of using and implementing a medical mobile phone app (QUiPP V2) designed to predict the risk of preterm birth and aid clinical decision making

BMC Medical Informatics and Decision Making, 2021
Background As the vast majority of women who present in threatened preterm labour (TPTL) will not deliver early, clinicians need to balance the risks of over-medicalising the majority of women, against the potential risk of preterm delivery for those ...
N. Carlisle, H. A. Watson, J. Carter, K. Kuhrt, P. T. Seed, R. M. Tribe, J. Sandall, A. H. Shennan   +7 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Benchmarking survival machine learning models for 10-year cardiovascular disease risk prediction using large-scale electronic health records

Digital Health
Objective To evaluate the performance of machine learning (ML)-based survival models for 10-year cardiovascular disease (CVD) risk prediction using large-scale electronic health records (EHRs).
Tianyi Liu, Andrew Krentz, Lei Lu, Yanzhong Wang, Vasa Curcin   +4 more
doaj   +1 more source