Results 111 to 120 of about 1,910,644 (290)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Land use in life cycle assessment [PDF]

, 2011
As human population is continuously increasing, productive land is becoming even more limited resource for biomass production. Land use and land use change cause various environmental impacts. At the moment the focus is on land use related greenhouse gas
Antikainen, Riina, Helin, Tuomas, Mattila, Tuomas, Pingoud, Kim, Soimakallio, Sampo, Wessman, Helena   +5 more
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Adoption model of eco-friendly livestock innovation for beef cattle sustainability in dry climate regions

Environmental and Sustainability Indicators
Beef cattle farming plays an important role in improving rural economies, especially in arid climates that often face complex ecological, social and economic challenges.
Ture Simamora, Paulus Klau Tahuk, Muhamad Nasir Rofiq, Ody Wolfrit Matoneng, Stefanus Sio, Lalu Muhamad Risman Dwi Jumansyah, Brigida Antonia Correia, Ligia Tomas Correia   +7 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Performa Tungku Hibrid Energi Surya dan Gas untuk Alat Pengering Kabinet dengan Sistem Cerdas

Jurnal Ilmiah Rekayasa Pertanian dan Biosistem
Tujuan dari penelitian ini adalah untuk mengevaluasi kinerja alat pengering kabinet yang menggunakan hibrid energi surya dan LPG. Energi terbarukan sangat penting untuk pengeringan pertanian.
Indonesia Indonesia, Mursalim Mursalim, Anugerah Fitri Amalia   +2 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Blockchain and big data integration design for traceability and carbon footprint management in the fishery supply chain

Egyptian Informatics Journal
The utilization of blockchain technology in the fishing industry has been extensively studied and implemented to address issues such as illegal fishing and carbon emissions control.
Aslan Alwi, Nugroho Adi Sasongko, Suprapto, Yaya Suryana, Hendro Subagyo   +4 more
doaj   +1 more source

Life cycle assessment of three scenarios of cahrcoal production in the eastern amazon [PDF]

, 2011
The Amazon forest is well known for its wealth of resources. There is a great abundance of iron ore and wood. This situation has promoted the development of pig iron industries based on charcoal for their thermal processes.
Caldeira-Pires, Armando, Rodrigues, Thiago Oliveira, Rousset, Patrick   +2 more
core