Results 141 to 150 of about 533,744 (303)

Life Cycle Assessment

open access: yes
Life cycle ...
Shweta Singh, Satvasheel Powar
  +5 more sources

Performa Tungku Hibrid Energi Surya dan Gas untuk Alat Pengering Kabinet dengan Sistem Cerdas

open access: yesJurnal Ilmiah Rekayasa Pertanian dan Biosistem
Tujuan dari penelitian ini adalah untuk mengevaluasi kinerja alat pengering kabinet yang menggunakan hibrid energi surya dan LPG. Energi terbarukan sangat penting untuk pengeringan pertanian.
Indonesia Indonesia   +2 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Blockchain and big data integration design for traceability and carbon footprint management in the fishery supply chain

open access: yesEgyptian Informatics Journal
The utilization of blockchain technology in the fishing industry has been extensively studied and implemented to address issues such as illegal fishing and carbon emissions control.
Aslan Alwi   +4 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

First proposition to include an integrated indicator of soil quality within the life cycle assessment framework [PDF]

open access: yes, 2018
Integrating a soil quality indicator within the Life Cycle Assessment (LCA) is necessary to assess the impact of land use on ecosystem services and related area of protections.
Brauman, Alain   +4 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Showcasing life cycle management

open access: yes
Industries following a linear approach assume that ‘if they produce more, they will sell more’. As new trends in production and consumption models emerge due to growing social, environmental and economic pressures, the linear approach is being replaced ...
Cano Londoño, Natalia AndreaCA100002212947868020040454410000-0003-4828-6442da2e1992-e388-11ec-a039-aec0cdf8977c   +3 more
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

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