Results 101 to 110 of about 2,415,273 (347)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Quantifying Uncertainty for Early Life Cycle Cost Estimates [PDF]

open access: yes, 2013
Disclaimer: The views represented in this report are those of the authors and do not reflect the official policy position of the Navy, the Department of Defense, or the federal government.Excerpt from the Proceedings of the Tenth Annual Acquisition ...
Ferguson, Bob   +4 more
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Computer programs for estimating civil aircraft economics [PDF]

open access: yes
Computer programs for calculating airline direct operating cost, indirect operating cost, and return on investment were developed to provide a means for determining commercial aircraft life cycle cost and economic performance.
Maddalon, D. V.   +2 more
core   +1 more source

Life-Cycle Cost and Life-Cycle Assessment Analysis at the Design Stage of a Fiber-Reinforced Polymer-Reinforced Concrete Bridge in Florida

open access: yesAdvances in Civil Engineering Materials, 2019
To support and promote the deployment of innovative technologies in infrastructure, it is fundamental to quantify their implications in terms of both economic and environmental impacts.
Thomas Cadenazzi   +4 more
semanticscholar   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Customer life cycle cost accounting – conceptual assumptions for State Forests [PDF]

open access: yesZeszyty Teoretyczne Rachunkowości
Purpose: The main objective of the article is to establish the conceptual assumptions of customer life cycle cost accounting in light of the results of research and the operational context of the State Forests (Lasy Państwowe – LP).
Piotr Szczypa, Grzegorz Lew
doaj   +1 more source

Supply Chain Cost Management: A Life Cycle Perspective [PDF]

open access: yes, 2014
Recently, nearly all goods have been experiencing shrinking life cycles, and drastic changes in consumer demand have occurred. The challenges presented by this changing market can be successfully coped with through the appropriate use of supply chains ...
皆川 芳輝
core  

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

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