Results 81 to 90 of about 305,477 (300)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

The lighting system's Life Cycle Cost including light pollution and manufacturing CO2 emissions (beta)

open access: yes, 2022
This tool is a customized Life Cycle Cost calculator based on the National Agency for Public Procurement's of the Swedish government. Several improvements have been made.
Alejandro Sánchez de Miguel
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Optimising age-replacement and extended non-renewing warranty policies in lifecycle costing [PDF]

open access: yes, 2011
This paper analyses the life cycle cost of equipment protected by both base and extended warranty policies from a consumer's perspective. We assume that the equipment has two types of failure: minor and catastrophic.
Phil Longhurst   +4 more
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

LIFE CYCLE ANALYSIS (LCA) FOR SUSTAINABLE ARCHITECTURE [PDF]

open access: yes, 2011
Life Cycle Analysis (LCA), a kind of cradle–to–grave paradigm based instrumentfor measuring the product sustainability by analyzing energy, cost, and environ-mental impacts that would be spent and occur along the product–life–cycle, isone of mechanisms ...
Subadra Abioso, Wanita
core  

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick   +19 more
wiley   +1 more source

Whole of life cycle cost analysis in bridge rehabilitation

open access: yes, 2002
The report presents a methodology for whole of life cycle cost analysis of alternative treatment options for bridge structures, which require rehabilitation.

core  

A generic tool for cost estimating in aircraft design [PDF]

open access: yes, 2008
A methodology to estimate the cost implications of design decisions by integrating cost as a design parameter at an early design stage is presented. The model is developed on a hierarchical basis, the manufacturing cost of aircraft fuselage panels ...
Price, M. (author)   +28 more
core   +1 more source

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