Results 71 to 80 of about 305,477 (300)

A generic life cycle cost modeling approach for aircraft system

open access: yes, 2019
Life cycle cost (LCC) is truly representative to the total cost of an aircraft through its life cycle. It is usually used for estimating the cost-effectiveness of an aircraft design. For enabling LCC estimation at early stage, A LCC model have been being
Wang, J   +6 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Life-cycle assessment of buildings: a Review

open access: yes, 2009
Life-Cycle Assessment (LCA) is one of various management tools for evaluating environmental concerns. This paper reviews LCA from a buildings perspective.
Menzies, Gillian Frances   +5 more
core   +1 more source

Bridging product life cycle gaps in LCA & LCC towards a circular economy

open access: yes, 2022
S.354-357Life cycle gap analysis (LCGA) is a specific technique to interpret life cycle assessment (LCA) results from a circular economy (CE) perspective in order to identify potentials to further improve a product's sustainability.
Viere, Tobias, Dieterle, Michael
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Test Sequencing Problem Considering Life Cycle Cost Based on the Tests with Non-Independent Cost

open access: yesChemical Engineering Transactions, 2013
The previous diagnostic strategy considering life cycle cost is generated based on the assumption that the test placement costs are independent with each other. In this paper, the problem based on non-independent test cost is studied. A general algorithm
Z. Hu   +4 more
doaj   +1 more source

A framework for documenting and analyzing life-cycle costs using a simple network based representation [PDF]

open access: yes, 2003
The introduction of high reliability systems combined with new ways of operating complex systems, particularly in aircraft design and operation has received much attention in recent years.
Davis, Neil D.   +2 more
core  

Eco-efficiency in a circular economy from a products life cycle gap perspective

open access: yes, 2020
Life cycle gap analysis (LCGA) is a particular technique to interpret life cycle assessment (LCA) results from a circular economy (CE) perspective in order to identify potentials for further improvement of products sustainability (Dieterle, Schäfer and ...
Viere, Tobias, Dieterle, Michael
core   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

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