Results 71 to 80 of about 994,847 (335)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Implementation of life cycle costing for a commercial building: case of a residential apartment at Yogyakarta

open access: yesMATEC Web of Conferences, 2017
Analysis of a design process is very important in controlling the initial costs and future costs in possession of an investment project such as commercial building.
Kaming Peter F
doaj   +1 more source

Sustainability in the product design: A review of recent development based on LCA [PDF]

open access: yes, 2018
In order to achieve sustainable product design process, aspects such of environmental, economic and social should be balanced. This paper discussed on sustainability of product design, conceptual basis of life cycle assessment (LCA), review of LCA at ...
Hassan, Mohd Fahrul   +3 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Briefing Note 1A - Life-Cycle Costs Approach: Costing Sustainable Services [PDF]

open access: yes, 2011
This briefing note uses an accounting framework, the life-cycle costs approach (LCCA), to explain the main cost components for water and sanitation in rural and peri-urban areas. The briefing note explains the building blocks used in the LCCA, then shows

core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Life Cycle Assessment and Life Cycle Costing of a Greenhouse Culture Model for Litopenaeus vannamei

open access: yesFishes
Greenhouse aquaculture is an increasingly advanced practice in shrimp farming. This study employs Life Cycle Costing (LCC) and Life Cycle Assessment (LCA) to systematically evaluate the economic and environmental performance of greenhouse shrimp farming.
Yuzhen Wang   +5 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

The credibility of health economic models for health policy decision-making: the case of population screening for abdominal aortic aneurysm [PDF]

open access: yes, 2007
<i>Objectives</i>: To review health economic models of population screening for abdominal aortic aneurysm (AAA) among elderly males and assess their credibility for informing decision-making. <i>Methods</i>: A literature review
Briggs, A.H.   +4 more
core   +1 more source

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