Results 81 to 90 of about 897,525 (296)
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Life Cycle Assessment and Life Cycle Costing for PSS [PDF]
The increasing awareness towards sustainability issues from both practitioners and customers makes it necessary to adopt a lifecycle perspective since the design phase of PSSs. In this chapter, a tool aimed at carrying out the Life Cycle Assessment (called MaGA) and one for the Life Cycle Costing (called BAL.LCPA) are introduced starting from the ...
Corti, Donatella +4 more
openaire +2 more sources
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
How Traditional Costing Methods Hinder the Development of Modular Product Architectures
This study investigates how traditional costing methods hinder the development of modular product architectures. A structured literature review identifies the gap between Management Accounting (MA) and Innovation and Operations Management (IOM ...
Morten Nørgaard +3 more
doaj +1 more source
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
THE DEVELOPMENT OF SUSTAINABLE DESIGN DECISION TOOL FOR PUBLIC BUILDINGS IN INDONESIA
Sustainable building has become a catchphrase in many countries. Issue on sustainability has attracted researchers from industry and academia in recent years, and the number is still growing. Despite different definitions of sustainable building, quality
Hamdi Akmal Lubis
doaj +1 more source
The University of British Columbia has an interest in incorporating life cycle environmental impacts and financial information into project planning, as well as research and teaching.
Zahra Teshnizi +4 more
semanticscholar +1 more source
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Agricultural life cycle assessment: a system-wide bibliometric research
Purpose. This paper aims to give a system-wide overview of agricultural life cycle assessment (LCA), based on the understanding of agriculture as a complex providing humanity with food, energy and other vital resources and considering all forms of sector’
Inna Koblianska +2 more
doaj +1 more source

