Mechanoregulatory Effects of Cell‐Scale Microwells on Epithelial Cell Phenotype
Advanced Functional Materials, EarlyView.In small polycaprolactone microwells, A549 epithelial cells span well edges, in contrast to cells growing on flat substrates. Focal adhesion sites (yellow) concentrate at topographic boundaries, while cytoskeletal tension (magenta stress fibers) is transmitted to the nucleus (blue), reducing nuclear sphericity.
Ruiwen He +10 more
wiley +1 more source
Cost-utility analysis of lenvatinib and sorafenib for the first-line treatment of unresectable hepatocellular carcinoma in Vietnam: Evidence from a lower-middle income country. [PDF]
PLoS OneDo TX +5 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat +11 more
wiley +1 more source
Evolutionary bioenergetics of sporulation. [PDF]
Proc Natl Acad Sci U S AKarakoç C, Shoemaker WR, Lennon JT.
europepmc +1 more source
Advanced Functional Materials, EarlyView.Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco +7 more
wiley +1 more source
Prediction of Relapse Using Digital Technology in People in Recovery From Substance Use Disorders: Early Economic Evaluation With a Case Study of the Subreal App. [PDF]
JMIR Form ResBouttell J, Bartler M, Bolton S.
europepmc +1 more source
Advanced Functional Materials, EarlyView.ABSTRACT Breathable membranes that reject chemical warfare agents (CWAs) are required for next‐generation protective apparel. A dual‐function graphene oxide (GO)‐polyamine architecture is introduced that addresses the long‐standing tradeoff between vapor transmission and CWA selectivity.
Hyungjun Kim +6 more
wiley +1 more source
Cost-effectiveness of microprocessor-controlled prosthetic knees in the Dutch healthcare system: The impact of study duration on outcomes. [PDF]
Can Prosthet Orthot JKuhlmann A, Kannenberg A.
europepmc +1 more source
Additive Manufacturing of NiTi Shape Memory Alloys for Elastocaloric Applications: A Review
Advanced Functional Materials, EarlyView.Additive manufacturing enables complex NiTi architectures that overcome key limitations in elastocaloric refrigeration, including poor heat transfer and high mechanical work input. This review surveys recent advances in LPBF‐ and DED‐fabricated NiTi shape memory alloys for elastocaloric applications, highlighting process–structure–performance ...
Ignatius Andre Setiawan +7 more
wiley +1 more source
The Hidden Cost of Precision: Financial, Training, and Environmental Trade-Offs in Robotic HPB Surgery. [PDF]
J Robot SurgHabash B.
europepmc +1 more source