Results 41 to 50 of about 195,446 (304)

Life cycle oriented milling tool management in small scale production

open access: yes, 2022
293298The milling technology is characterized as the most important manufacturing technology in a variety of industries. Moreover, recent developments in hardware and software issues have increased technology's complexity which is, beyond others, caused ...
Klocke, Fritz   +2 more
core   +1 more source

Implementation of life cycle costing for a commercial building: case of a residential apartment at Yogyakarta

open access: yesMATEC Web of Conferences, 2017
Analysis of a design process is very important in controlling the initial costs and future costs in possession of an investment project such as commercial building.
Kaming Peter F
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Comparative life cycle costs for new steel portal frame building systems

open access: yes, 2002
Life cycle costs of a new steel portal frame building system incorporating energy efficient sandwich panels are compared with those of a conventional steel portal frame building system for use in industrial and commercial buildings. The economic benefits
Mahendran, Mahen, Gurung, Netra
core   +1 more source

Life cycle profit optimization a business opportunity [PDF]

open access: yes, 2018
Life Cycle Profitability combines financial data, and forecasts, with market research to guide pricing decisions and to evaluate the cash flow consequences of goods and services.
Hunkeler, David
core   +1 more source

Analysis of the Cost of a Building’s Life Cycle in a Probabilistic Approach

open access: yesOpen Engineering, 2019
In the article the costs of alternative roofing techniques in the life cycle of the building were calculated. The calculations were made in accordance with ISO 15686-5 standard “Buildings and constructed assets – Service life planning – Part 5: Life ...
Rogalska M., Szewczak D.
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Practitioners' use of life cycle costing with environmental costs—a Swedish study

open access: yes, 2011
The aim of this paper is to describe life cycle costing (LCC) practices in some Swedish organisations, investigate probable changes and determine whether and how environmental costs (internal and/or external) are considered in current LCC.
Hochschorner, Elisabeth,   +3 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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