Results 181 to 190 of about 13,140,877 (372)
Concordance between GeneXpert and Life Real Detection Kit in the diagnosis of acute respiratory infections [PDF]
, 2023 Celia García-Rivera +3 more
openalex +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Triaxial Accelerometer-Based Falls and Activities of Daily Life Detection Using Machine Learning. [PDF]
Sensors (Basel), 2020 Althobaiti T, Katsigiannis S, Ramzan N.
europepmc +1 more source
P3‐170: DECREASED PHYSICAL HEALTH AND ENVIRONMENTAL DOMAINS OF QUALITY OF LIFE (WHOQOL‐BREF) IN MILD COGNITIVE IMPAIRMENT: IMPLICATIONS FOR GENDER‐DIFFERENT EARLY DETECTION IN THE COMMUNITY–THE TOME PROJECT [PDF]
, 2014 Mari Kasai +8 more
openalex +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
A Personalized Approach to Improve Walking Detection in Real-Life Settings: Application to Children with Cerebral Palsy [PDF]
, 2019 Léna Carcreff +5 more
openalex +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source