Results 131 to 140 of about 1,707,049 (269)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Health-Related Quality of Life Evaluation in Children with Cochlear Implants. [PDF]

J Int Adv Otol
Tulaci T, Ceylan BT, Mutlu M, Gokce Tulaci K, Akin İ, Ozdek A.   +5 more
europepmc   +1 more source

A Thermo-Mechanical Stress Based Fatigue Life Evaluation of a Mine Hoist Drum Brake System Using COMSOL Multiphysics. [PDF]

Materials (Basel), 2022
Radu SM, Popescu FD, Andraș A, Virág Z, Brînaș I, Draica MI.   +5 more
europepmc   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Health-related quality-of-life evaluation in epidermolysis bullosa: a scoping review protocol. [PDF]

Syst Rev
Arias-Merino G, Benito-Lozano J, Linertová R, Alonso-Ferreira V, on behalf the BUR-EB Study Group.   +4 more
europepmc   +1 more source

Shelf-Life Evaluation of Ingredient Combinations and Technologies for Use in Pet Food Formulations. [PDF]

Animals (Basel), 2022
Wagoner MP, Presume MR, Chilenje ME, Abascal-Ponciano GA, Sandoval JL, Smith HR, Reyes TM, Wilborn BS, Dunavant JA, Mason RP, Altom EK, Starkey CW, Sawyer JT.   +12 more
europepmc   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Multicenter real-life evaluation of the Post-CAR prognostic index for patients with large B-cell lymphoma after CAR-T failure. [PDF]

J Hematol Oncol
Farina M, Maiolo E, Ghiggi C, Angelillo P, Novo M, Quaglia FM, Schiattone L, Battista ML, Mannelli L, Tomarchio V, Lucchini E, Pagliaro L, Scapinello G, Marangon M, Pelliccia S, Sciarra R, Russo D, Zaja F.   +17 more
europepmc   +1 more source

Early Childhood Caries and Oral Health-Related Quality of Life: Evaluation of the Effectiveness of Single-Session Therapy Under General Anesthesia. [PDF]

Eur J Dent, 2023
Ludovichetti FS, Zuccon A, Cantatore D, Zambon G, Girotto L, Lucchi P, Stellini E, Mazzoleni S.   +7 more
europepmc   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source