This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Postoperative rehabilitation and quality of life evaluation for transoral endoscopic thyroidectomy vestibular approach. [PDF]
Mao Y +9 more
europepmc +1 more source
Service Life Evaluation for RC Sewer Structure Repaired with Bacteria Mixed Coating: Through Probabilistic and Deterministic Method. [PDF]
Yoon HS, Yang KH, Lee KM, Kwon SJ.
europepmc +1 more source
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Effectiveness and tolerability of givosiran for the management of acute hepatic porphyria: A monocenter real-life evaluation. [PDF]
Guida CC +8 more
europepmc +1 more source
Biodegradation of crude oil by immobilized Exiguobacterium sp. AO-11 and shelf life evaluation. [PDF]
Sakdapetsiri C, Kaokhum N, Pinyakong O.
europepmc +1 more source
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Improved Patient-Reported Outcomes With Post-Transplant Cyclophosphamide: A Quality-of-Life Evaluation and 2-Year Outcomes of BMT CTN 1703. [PDF]
Holtan SG +31 more
europepmc +1 more source
A multicenter randomized trial for quality of life evaluation by non-invasive intelligent tools during post-curative treatment follow-up for head and neck cancer: Clinical study protocol. [PDF]
Cavalieri S +23 more
europepmc +1 more source

