Results 201 to 210 of about 7,129,302 (338)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Parental altruism, life expectancy and dynamically inefficient equilibria [PDF]

Macrodynamic models with finite lifetime and selfish individuals may feature (dynamically) inefficient equilibria, while models with infinite lifetime and altruistic individuals cannot.
d'Albis, Hippolyte, Decreuse, Bruno
core   +1 more source

Revisiting National Life Expectancy: The Effect of Including Prenatal Deaths in Canada. [PDF]

Linacre Q
Jamil U, Pearce JM.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Job control and working life expectancy in Sweden [PDF]

Eur J Public Health
Almroth M, Nevriana A, Falkstedt D, Burdorf A, Kjellberg K, Hemmingsson T, Pan KY, Pedersen J.   +7 more
europepmc   +2 more sources

Genetic Variants Associated with Life Expectancy in Patients with Chagas Disease. [PDF]

Med Sci (Basel)
Principato MB, Carvelli MV, Paolucci A, Principato C, Villa Fernandez R, Aguirre N, Ercoli G, Keller GA, Di Girolamo G, Lago M, Carbajales J.   +10 more
europepmc   +1 more source

Life expectation

, 2019
The survey conducted by EU/Public Opinion shows that people’s general life expectancy for the next year in Turkey and EU. This report represents the steep changes, remarkable rates and comparison between Turkey’s and EU countries’ results according to socioeconomic incidents.
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Age-specific Income Inequality and Life Expectancy: New Evidence [PDF]

Objectives -- The study has two primary goals. First, to test the hypothesis that higher levels of income inequality are related to lower levels of population health with updated data from around year 2000.
Robert L. Brown, Steven G. Prus
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source