Results 201 to 210 of about 263,133 (259)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Life expectancy after kidney transplantation in a population-based retrospective cohort. [PDF]

Sci Rep
Babich T, Daitch V, Leibovici L, Green H, Turjeman A.   +4 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Changes in life expectancy and life span equality during the COVID-19 epidemic in 2020-22 in Japan. [PDF]

PLoS One
Okada Y, Nishiura H.
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

The geography of American longevity: structural determinants of a 20-year life expectancy divide and a federal policy blueprint. [PDF]

Front Public Health
Niazi SK.
europepmc   +1 more source

Valuing Mortality Risk Reductions and Health Improvements: A Life Expectancy Framework to Harmonize Policy Traditions. [PDF]

Risk Anal
Nielsen JS, Chilton S, McDonald R.
europepmc   +1 more source

Healthy dietary patterns, longevity genes, and life expectancy: A prospective cohort study. [PDF]

Sci Adv
Lv Y, Song J, Ding D, Luo M, He FJ, Yuan C, MacGregor GA, Liu L, Chen L.   +8 more
europepmc   +1 more source

Beyond health economics: economic growth, artificial intelligence, and environmental externalities in shaping life expectancy. [PDF]

Front Public Health
Ageli MM.
europepmc   +1 more source