Results 91 to 100 of about 10,978,714 (364)
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri+5 more
wiley +1 more source
Two new species of the Indo-Australian genus Pelagodes Holloway, 1996 are described as new. Pelagodes sebastiani Lindt, Lennuk & Viidalepp, sp. nov. resembles Pelagodes rana Holloway, 1996 in the shape of its frog-leglike appendages on the male eighth ...
Aare Lindt+2 more
doaj +1 more source
The Anchonini known from Africa are reviewed. The monotypic genus Aethiopacorep is redescribed. The new West African genus Titilayo gen. nov. is described, with seven new species: four from São Tomé, T. perrinae sp. nov., T. saotomense sp.
Joana P. Cristóvão+1 more
doaj +1 more source
The influence of humidity on the life history of mosquitoes and on their power to transmit infection [PDF]
C. A. Gill
openalex +1 more source
Protein kinase FAM20C—when subcellular localization matters
FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source
Background Accurate diagnosis of urogenital schistosomiasis is vital for surveillance/control programs. Amplification of schistosome DNA in urine by PCR is sensitive and specific but requires infrastructure, financial resources and skilled personnel ...
A. Rosser+3 more
doaj +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Rhodochlora Warren, 1894 is a Neotropical genus of the largest and most attractive species of their kind. This article aims to characterize two additional species.
Jaan Viidalepp+2 more
doaj +1 more source