Results 91 to 100 of about 10,978,714 (364)

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

Two new species of Pelagodes Holloway, 1996 from Eastern New Guinea (Lepidoptera: Geometridae, Geometrinae, Thalassodini)

open access: yesSHILAP
Two new species of the Indo-Australian genus Pelagodes Holloway, 1996 are described as new. Pelagodes sebastiani Lindt, Lennuk & Viidalepp, sp. nov. resembles Pelagodes rana Holloway, 1996 in the shape of its frog-leglike appendages on the male eighth ...
Aare Lindt   +2 more
doaj   +1 more source

Anchonini in Africa: New Species and Genus Confirming a Transatlantic Distribution (Coleoptera: Curculionidae: Molytinae)

open access: yesDiversity, 2018
The Anchonini known from Africa are reviewed. The monotypic genus Aethiopacorep is redescribed. The new West African genus Titilayo gen. nov. is described, with seven new species: four from São Tomé, T. perrinae sp. nov., T. saotomense sp.
Joana P. Cristóvão   +1 more
doaj   +1 more source

Protein kinase FAM20C—when subcellular localization matters

open access: yesFEBS Letters, EarlyView.
FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley   +1 more source

Isothermal Recombinase Polymerase amplification (RPA) of Schistosoma haematobium DNA and oligochromatographic lateral flow detection

open access: yesParasites & Vectors, 2015
Background Accurate diagnosis of urogenital schistosomiasis is vital for surveillance/control programs. Amplification of schistosome DNA in urine by PCR is sensitive and specific but requires infrastructure, financial resources and skilled personnel ...
A. Rosser   +3 more
doaj   +1 more source

The Life History of the Termite [PDF]

open access: yesScientific American, 1909
n ...
openaire   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Two new species of Rhodochlora Warren, 1894 of the Neotropics (Lepidoptera: Geometridae, Geometrinae)

open access: yesSHILAP
Rhodochlora Warren, 1894 is a Neotropical genus of the largest and most attractive species of their kind. This article aims to characterize two additional species.
Jaan Viidalepp   +2 more
doaj   +1 more source

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