Results 91 to 100 of about 6,579,623 (306)

Speaking about things: oral history as context [PDF]

open access: yes, 2007
‘Speaking About Things: Oral History as Context’ draws on life history interviews conducted under the auspices of two oral history projects: the Life Story Collection at The British Library National Sound Archive [2003-4] [LSC], and the Voices in the ...
Sandino, Linda
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

First karyological analysis of the endemic Malagasy phantom gecko Matoatoa brevipes (Squamata: Gekkonidae)

open access: yesActa Herpetologica, 2020
The genus Matoatoa includes two Malagasy endemic species, M. brevipes and M. spannringi. Due to their cryptic behaviour, the two species are known only from a handful of specimens and have been included in few molecular studies.
Marcello Mezzasalma   +5 more
doaj   +1 more source

Pedagogical potential of narrative and life history research in education [PDF]

open access: yes, 2017
This paper aims to explore and reflect on the pedagogical potential of the narrative and biographical research methodology in education to illuminate and address issues related with immigration, inclusion and social justice.
Herrera Pastor, David, Mancila, Iulia
core  

A new species of Polyphylla Harris from peninsular Florida (Coleoptera: Scarabaeidae: Melolonthinae) with a key to species of the pubescens species group [PDF]

open access: yes, 2009
Polyphylla starkae Skelley, new species (Coleoptera: Scarabaeidae: Melolonthinae: Melolonthini), is described from peninsular Florida, USA.
Skelley, Paul E.
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Life history and ecological genetics of the colonial ascidian Botryllus schlosseri [PDF]

open access: yes, 2015
The colonial ascidian Botryllus schlosseri is a cosmopolitan, marine filter feeder, introduced as a laboratory research organism in the 1950s. Currently, it is widely used in many laboratories to investigate a variety of biological questions.
Ballarin, Loriano   +7 more
core   +1 more source

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