Results 121 to 130 of about 15,495,313 (386)

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Isothermal Recombinase Polymerase amplification (RPA) of Schistosoma haematobium DNA and oligochromatographic lateral flow detection

Parasites & Vectors, 2015
Background Accurate diagnosis of urogenital schistosomiasis is vital for surveillance/control programs. Amplification of schistosome DNA in urine by PCR is sensitive and specific but requires infrastructure, financial resources and skilled personnel ...
A. Rosser, D. Rollinson, M. Forrest, B L Webster   +3 more
doaj   +1 more source

From organism to population: the role of life-history theory [PDF]

, 1994
The role of life-history theory in population and evolutionary analyses is outlined. In both cases general life histories can be analysed, but simpler life histories need fewer parameters for their description.
Sibly, R.M.
core  

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Two new species of Pelagodes Holloway, 1996 from Eastern New Guinea (Lepidoptera: Geometridae, Geometrinae, Thalassodini)

SHILAP
Two new species of the Indo-Australian genus Pelagodes Holloway, 1996 are described as new. Pelagodes sebastiani Lindt, Lennuk & Viidalepp, sp. nov. resembles Pelagodes rana Holloway, 1996 in the shape of its frog-leglike appendages on the male eighth ...
Aare Lindt, Lennart Lennuk, Jaan Viidalepp   +2 more
doaj   +1 more source

Anchonini in Africa: New Species and Genus Confirming a Transatlantic Distribution (Coleoptera: Curculionidae: Molytinae)

Diversity, 2018
The Anchonini known from Africa are reviewed. The monotypic genus Aethiopacorep is redescribed. The new West African genus Titilayo gen. nov. is described, with seven new species: four from São Tomé, T. perrinae sp. nov., T. saotomense sp.
Joana P. Cristóvão, Christopher H. C. Lyal   +1 more
doaj   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

An Interview About an Illness [PDF]

, 2009
The respondent tells of his experience of a life-threatening illness.The fifty one audio and nine video files in this collection include: villages’ life stories, circle-dancing songs and performance, local history, folk tales, and interviews from ...
G.yu lha
core  

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

FEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu, Takayuki Sadakane, Yudai Murata, Junichi Taira, Hiroshi Sakamoto, Takao Kodama   +5 more
wiley   +1 more source

Two new species of Rhodochlora Warren, 1894 of the Neotropics (Lepidoptera: Geometridae, Geometrinae)

SHILAP
Rhodochlora Warren, 1894 is a Neotropical genus of the largest and most attractive species of their kind. This article aims to characterize two additional species.
Jaan Viidalepp, Lennart Lennuk, Aare Lindt   +2 more
doaj   +1 more source