Results 181 to 190 of about 8,942,242 (366)

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Compilation of Load Spectrum of Loader Working Device and Application in Fatigue Life Prediction. [PDF]

Sensors (Basel)
Shi X, Guo W, Wang J, Li G, Lu H.
europepmc   +1 more source

Prediction of health-related quality-of-life results after lung stereotactic body radiotherapy using dose-volume parameters from functional mapping on Gallium-68 perfusion PET/CT [PDF]

François Lucia, Jacqueline M. Lamour, Margaux Geier, Vincent Bourbonne, Fanny Pinot, Malik Nebbache, Frédérique Blanc-Béguin, Simon Hennebicq, Maëlle Mauguen, K. Kerleguer, Ulrike Schick, Olivier Pradier, Grégoire Le Gal, Pierre‐Yves Salaün, David Bourhis, Pierre‐Yves Le Roux   +15 more
openalex   +1 more source

Numerical prediction of fretting fatigue life for cold-drawn eutectoid carbon steel wire using continuum damage mechanics and effective slip amplitude

, 2023
Zhen Hu, Yixuan Hou, Enyuan Wang, Jia Fu-yin, Reza Talemi   +4 more
openalex   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Interpretable ensemble remaining useful life prediction enables dynamic maintenance scheduling for aircraft engines. [PDF]

Sci Rep
Özcan H.
europepmc   +1 more source

Digital Twin and Data-Driven Remaining Useful Life Prediction of Gearbox

Quanbo Lu, Mei Li, Xiaojuan Huang
openalex   +1 more source

Fatigue life prediction and performance index evaluation of SEPS block-copolymers and advanced TPU for the design of a trileaflet Prosthetic Heart Valve [PDF]

, 2016
Eugenia Biral
openalex  

Ensemble Neural Networks for Remaining Useful Life (RUL) Prediction

, 2023
Abhishek Srinivasan, Juan Carlos Andresen, Anders G. Holst   +2 more
openalex   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source