Results 61 to 70 of about 16,357,515 (337)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

The Life Satisfaction Approach to Environmental Valuation [PDF]

open access: yes
In many countries environmental policies and regulations are implemented to improve environmental quality and thus individuals' well-being. However, how do individuals value the environment?
Stutzer, Alois   +2 more
core   +4 more sources

Determinants of Happiness and Life Satisfaction: The Life Satisfaction Survey of the Turkish Statistical Institute

open access: yesSosyal Siyaset Konferansları Dergisi, 2021
The main focus area of economic science is the welfare and well-being of individuals in society. This requires measuring factors and monitoring their progress over time.
Sema Ulutürk Akman
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Life satisfaction of Lublin nurses

open access: yesJournal of Education, Health and Sport, 2017
Introduction. Life satisfaction is a concept closely related to a feeling of happiness, well-being and comfort. It is felt by every man individually and is related to general evaluation of life.
Klaudia Olga Jakubowska   +3 more
doaj   +3 more sources

Life Satisfaction and Work-Related Satisfaction among Anesthesiologists in Poland

open access: yesThe Scientific World Journal, 2014
The aim of the study was to assess the level of life and job satisfaction of Polish anesthesiologists and to explore the impact of extrinsic-hygiene and intrinsic-motivating determinants. Materials and Methods.
Ewelina Gaszynska   +4 more
doaj   +1 more source

The structure of psychological life satisfaction: insights from farmers and a general community sample in Australia

open access: yesBMC Public Health, 2012
Background Psychological life satisfaction is a robust predictor of wellbeing. Public health measures to improve wellbeing would benefit from an understanding of how overall life satisfaction varies as a function of satisfaction with multiple life ...
OBrien Léan V   +2 more
doaj   +1 more source

Mediating roles of perceived social support and sense of security in the relationship between negative life events and life satisfaction among left-behind children: A cross-sectional study

open access: yesFrontiers in Psychology, 2023
ObjectiveLife satisfaction is closely related to the quality of life. Previous studies showed that left-behind children have low life satisfaction levels due to their separation from their parents. Therefore, it is significant to explore the risk factors
Na Liu   +4 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Do wage and wage satisfaction compensate for the effects of a dissatisfying job on life satisfaction?

open access: yesSA Journal of Industrial Psychology, 2019
Orientation: Research regarding subjective well-being (including life satisfaction and domain-specific satisfaction) is necessary, given the effects thereof on health, work performance, social relationships and ethical behaviour of employees.
Jacob A. de Coning   +2 more
doaj   +1 more source

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