Results 91 to 100 of about 8,033,101 (355)

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Science, ideology and daily life

open access: yesJournal of Innovation & Knowledge, 2018
Despite years of scientific effort to develop useful and safe biotech crops, ideologies have prevailed and genetically modified (GM-)crops have still not been fully accepted by today's society. This leads one to reflect on the role of Science in society,
Marc Van Montagu
doaj   +1 more source

Sources Of Student Engagement In Introductory Physics For Life Sciences [PDF]

open access: yes, 2018
We explore the sources of student engagement with curricular content in an Introductory Physics for Life Science (IPLS) course at Swarthmore College. Do IPLS students find some life-science contexts more interesting than others, and, if so, what are the ...
Crouch, Catherine Hirshfeld   +2 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Why emerging leaders should focus on being good postdoctoral supervisors

open access: yesFEBS Letters, EarlyView.
Swamped with work and suddenly a new student is waiting at your doorstep for supervision? Great—this is your chance! In this article, we share tips on how postdocs can strengthen their leadership skills while supervising students. This image has been created using DALL·E. Many postdocs work as leaders later in their career.
Hannah Rostalski   +5 more
wiley   +1 more source

PENGEMBANGAN LKPD Qr Code IPA PADA MATERI TUMBUHAN SUMBER KEHIDUPAN DI BUMI MATA PELAJARAN IPAS KELAS IV SD [PDF]

open access: yes
Based on the results of the analysis of grade IV students, teachers do not use technology during learning so that the learning carried out in class is monotonous even though students are familiar with technology.
Setya Ningrum, Zakia Nuramalia
core  

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Partnering with Life Science Alliance

open access: yesMolecular Systems Biology, 2018
Molecular Systems Biology is partnering with the new open‐access journal Life Science Alliance, an initiative by three major not‐for‐profit science organizations. An informed transfer process was established with our partner to provide authors with clear
Thomas Lemberger
doaj   +1 more source

Relevance of Life-Cycle Assessment in Context-Based Science Education: A Case Study in Lower Secondary School [PDF]

open access: gold, 2019
Sakari Tolppanen   +4 more
openalex   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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