Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Prevalence of major diseases in common marmosets (<i>Callithrix jacchus</i>) at the Central Institute for Medicine and Life Science: a retrospective study. [PDF]
Mineshige T +5 more
europepmc +1 more source
Evaluating a Novel Gas Sensor for Ambient Monitoring in Automated Life Science Laboratories. [PDF]
Al-Okby MFR +3 more
europepmc +1 more source
Perceived distance and instructional design in online agriculture and life science courses
Yahya S. Alotibi
openalex +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
An exploratory study combining Virtual Reality and Semantic Web for life science research using Graph2VR. [PDF]
Kellmann AJ +8 more
europepmc +1 more source
Ion-Exchange Chromatography Coupled to Mass Spectrometry in Life Science, Environmental, and Medical Research. [PDF]
Ngere JB +5 more
europepmc +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source

