Results 261 to 270 of about 8,207,011 (340)

Life Science

open access: yesTRENDS IN THE SCIENCES, 2002
openaire   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Breaking the mold with RNA-a "RNAissance" of life science. [PDF]

open access: yesNPJ Genom Med
Jones CH   +8 more
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Using a 'Students as Partners' model to develop an authentic assessment promoting employability skills in undergraduate life science education. [PDF]

open access: yesFEBS Open Bio
Van K   +8 more
europepmc   +1 more source

Parallel Algorithms for Multirelational Data Mining: Application to Life Science Problems

open access: gold, 2016
Rui Camacho   +5 more
openalex   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Bio-based polylactic acid labware as a sustainable alternative for microbial cultivation in life science laboratories. [PDF]

open access: yesHeliyon
O Loughlin J   +8 more
europepmc   +1 more source

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