Results 81 to 90 of about 8,033,101 (355)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Reliable and robust robotic handling of microplates via computer vision and touch feedback

open access: yesFrontiers in Robotics and AI
Laboratory automation requires reliable and precise handling of microplates, but existing robotic systems often struggle to achieve this, particularly when navigating around the dynamic and variable nature of laboratory environments. This work introduces
Vincenzo Scamarcio   +3 more
doaj   +1 more source

Information Science and Philosophy [PDF]

open access: yes, 2018
Looking out of Information Science (IS) it´s a dangerous attempt to compare this relative new science direct with Philosophy. Here you find a first circumspective trial of an investigation of the traditionally named “queen of science”, Philosophy, two ...
Plochberger, Franz
core   +1 more source

Life in Science and the Science of Life by Aleksandr Shmuk

open access: yesNasledie Vekov, 2020
Рецензируется книга доктора биологических наук, академика РАН А.Х. Шеуджена и доктора исторических наук А.Н. Еремеевой, посвященная жизни и творчеству известного советского агрохимика и биохимика, академика ВАСХНИЛ Александра Александровича Шмука (1886–1945). Анализ отечественной и зарубежной литературы, научных и общественно-политических периодических
openaire   +2 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Single-sex schools and science engagement [PDF]

open access: yes
This paper considers whether single-sex schooling affects gendered patterns in the uptake of science courses in year 11 and the development of science-related career paths.
Joanna Sikora
core  

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

The life devoted to science

open access: yesІнтродукція Рослин, 2010
The life and scientific work botanist, brooder of fruit plants S.V. Klymenko are retraced.
N.V. Chuvikina
doaj   +1 more source

Genetic basis of between-individual and within-individual variance of docility [PDF]

open access: yes, 2017
Funded by Alces Software UCLA Academic Senate Division of Life Sciences National Geographic Society National Science Foundation. Grant Numbers: IDBR-0754247, DEB-1119660, DBI-0242960, DBI-0731346 University of Aberdeen Data deposited at Dryad: doi:10 ...
Blumstein, D T   +3 more
core   +1 more source

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