Results 91 to 100 of about 2,956,560 (314)

Towards Research Excellence and Innovation Capacity in Studing Lake Ecosystems Functional Structures and Climate Change Impact – TREICLAKE : [presentation] [PDF]

open access: yes, 2022
Objectives: to improve/icrease in EMU Chair of hydrobiology and fisheries 1. Scientific Expertise 2. Scientific Infrastructure (mesocosm facility) 3. Impact in the Scientific Community 4. Management and administration skills 5.
Estonian University of Life Sciences
core  

Science - Sense of Life [PDF]

open access: yesEuropean Financial and Accounting Journal, 2009
Dear readers, European Financial and Accounting Journal boasts about attribute "scientific". Therefore let me put a question whether people thirst for science. Most of us probably answered yes. From medical sciences we expect new remedies for old and new diseases, from technical research we hope for new inventions which will make our labor and personal
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

When Life Science Meets Educational Robotics: A Study of Students’ Problem Solving Process in a Primary School

open access: yesEducational Technology & Society, 2022
Previous studies on the topic of “Problem solving” indicate it’s one of the skills of students in the 21st century that educational robots can effectively support. Additionally, there are gender differences in the problem-solving process.
Yulong Sun   +2 more
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Gender Inequity during the Ph.D.: Females in the Life Sciences Benefit Less from Their Integration into the Scientific Community

open access: yesSocial Sciences, 2018
Female researchers remain underrepresented in higher academic ranks, even within female-dominated fields, such as the life sciences. The phenomenon is often attributed to women’s lower publication productivity.
Nurith Epstein, Daniel Lachmann
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Des bio-objets pour la bioéthique. Compte rendu de Bio-Objects: Life in the 21st Century

open access: yesBioéthiqueOnline, 2014
The collective work Bio-Objects: Life in the 21st Century, edited by Niki Vermeulen, Saka Tamminen and Andrew Webster analyzes new forms of life arising from the biosciences in terms of their bio-objectification.
Couture, Vincent
doaj  

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