Louis Agassiz, a Life in Science, by Edward Lurie [Review]
, 1961 J. Walton Groves
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Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Leonid Ilyich Brezhnev: A Short Biography. By the Institute of Marxism-Leninism, CPSU Central Committee. Leaders of the World Biographical Series. New York: Pergamon Press, 1977. xiv, 240 pp. Photographs. $10.00. - Leonid I. Brezhnev: Pages From his Life. Written under the auspices of the Academy of Sciences of the USSR. Foreword by Leonid I. Brezhnev. New York: Simon and Schuster, 1978. 320 pp. + 40 pp. plates. $11.95. [PDF]
, 1979 Robert H. McNeal
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Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Mary P. Winsor, Starfish, jellyfish, and the order of life. Issues in nineteenthcentury science, New Haven, Conn., and London, Yale University Press, 1976, 8vo, pp. [5 11], 228, illus., £10.50. [PDF]
, 1977 openalex +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source