Results 211 to 220 of about 15,808,373 (394)

2. Innovation of Life Science through Digital Transformation Focused on AI-driven Technologies

, 2023
Yasushi Okada
openalex   +2 more sources

Deuterium- and Tritium-Labelled Compounds: Applications in the Life Sciences.

Angewandte Chemie, 2018
Jens Atzrodt, Volker Derdau, W. Kerr, M. Reid   +3 more
semanticscholar   +1 more source

The 1984 NASA/ASEE summer faculty fellowship program [PDF]

An overview is given of the program management and activities. Participants and research advisors are listed. Abstracts give describe and present results of research assignments performed by 31 fellows either at the Johnson Space Center, at the White ...
Crow, B., Duke, M. B., Mcinnis, B. C.
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

RDMkit: A research data management toolkit for life sciences. [PDF]

Patterns (N Y)
Alper P, D'Anna F, Droesbeke B, Andrabi M, Andrade Buono R, Bianchini F, Bösl K, Chandramouliswaran I, Cook M, Faria D, Fatima N, Hooft R, Jareborg N, Jetten M, Pilvar D, Poires-Oliveira G, Popleteeva M, Portell-Silva L, Slifka J, Suchánek M, van Gelder C, Welter D, Wittig U, Coppens F, Goble C.   +24 more
europepmc   +1 more source

Publications of the space physiology and countermeasures program, Musculoskeletal Discipline: 1980-1990 [PDF]

A 10-year cumulative bibliography of publications resulting from research supported by the musculoskeletal discipline of the space physiology and countermeasures program of NASA's Life Sciences Division is provided.
Dickson, Katherine J., Hess, Elizabeth L., Powers, Janet V., Wallace-Robinson, Janice   +3 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Magnetic Nanoparticles: Synthesis and Applications in Life Sciences. [PDF]

ChemistryOpen
Chand K, Vasquez-Guardado ES.
europepmc   +1 more source

The Literature of the Life Sciences: Reading, Writing, Research.

, 1985
Brodman, Estelle
openalex   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source