Results 231 to 240 of about 11,222,251 (340)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

PACIFIC NORTHWEST LABORATORY ANNUAL REPORT FOR 1970 TO THE USAEC DIVISION OF BIOLOGY AND MEDICINE. VOLUME i. LIFE SCIENCES. PART 2. ECOLOGICAL SCIENCES.

, 1971
B.E. Vaughan
openalex   +2 more sources

POLCAM: instant molecular orientation microscopy for the life sciences. [PDF]

Nat Methods
Bruggeman E, Zhang O, Needham LM, Körbel M, Daly S, Cheetham M, Peters R, Wu T, Klymchenko AS, Davis SJ, Paluch EK, Klenerman D, Lew MD, O'Holleran K, Lee SF.   +14 more
europepmc   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

PACIFIC NORTHWEST LABORATORY ANNUAL REPORT FOR 1970 TO THE USAEC DIVISION OF BIOLOGY AND MEDICINE. VOLUME I. LIFE SCIENCES. PART 1. BIOLOGICAL SCIENCES.

, 1971
R C Thompson
openalex   +2 more sources

Random walk models in the life sciences: including births, deaths and local interactions. [PDF]

J R Soc Interface
Plank MJ, Simpson MJ, Baker RE.
europepmc   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Pacific Northwest Laboratory annual report for 1972 to the USAEC Division of Biological and Environmental Research. Volume I. Life sciences. Part 1. Biological sciences

, 1973
R C Thompson
openalex   +2 more sources

Editorial: Revolutionizing life sciences: the nobel leap in artificial intelligence-driven biomodeling. [PDF]

Front Mol Biosci
Tozzini V, Giulivi C.
europepmc   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source