Results 81 to 90 of about 6,108,300 (348)

Life sciences flight experiments program, life sciences project division, procurement quality provisions [PDF]

open access: yes
Methods are defined for implementing quality assurance policy and requirements for life sciences laboratory equipment, experimental hardware, integration and test support equipment, and integrated ...
House, G.
core   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

Pragmatic, Interdisciplinary Perspectives on Blockchain and Distributed Ledger Technology: Paving the Future for Healthcare

open access: yesBlockchain in Healthcare Today, 2018
Background: Blockchain and distributed ledger technology is a disruptive force in healthcare. Methods: This article provides a globally relevant, interdisciplinary perspective intended to aid disparate group of actors, participants, and users that ...
Ron Ribitzky   +8 more
doaj   +1 more source

Recent Progress in Chirality Research Using Circularly Polarized Light [PDF]

open access: yesPhotochemistry: UV/VIS Spectroscopy, Photochemical Reactions and Photosynthesis: Nova Science Publishers (2011), pp.291-308, 2010
(abridged) We review recent studies of chirality using circularly polarized light, along with the birth and evolution of life and planetary systems. Terrestrial life consists almost exclusively of one enantiomer, left-handed amino acids. This characteristic feature is called homochirality, whose origin is still unknown.
arxiv  

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

The Chirality Of Life: From Phase Transitions To Astrobiology [PDF]

open access: yesarXiv, 2008
The search for life elsewhere in the universe is a pivotal question in modern science. However, to address whether life is common in the universe we must first understand the likelihood of abiogenesis by studying the origin of life on Earth. A key missing piece is the origin of biomolecular homochirality: permeating almost every life-form on Earth is ...
arxiv  

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Seasonal Goods and Spoiled Milk: Pricing for a Limited Shelf-Life [PDF]

open access: yesarXiv, 2018
We examine the case of items with a limited shelf-life where storing an item (before consumption) may carry a cost to a buyer (or distributor). For example, eggs, milk, or Groupon coupons have a fixed expiry date, and seasonal goods can suffer a decrease in value.
arxiv  

Science and Life [PDF]

open access: yesNature, 1954
The Nature of Science and Other Lectures By Edwin Hubble. Pp. viii + 83 + 2 plates. (San Marino, Calif.: The Huntington Library, 1954.) 2 dollars.
openaire   +2 more sources

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

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