Results 161 to 170 of about 17,023,679 (280)

Erratum to: Systems biology for molecular life sciences and its impact in biomedicine [PDF]

Cellular and Molecular Life Sciences, 2013
openaire   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Correction to: Engineered Alzheimer Organoids Validate the Link Between Intracellular and Soluble p-Tau Biomarkers and Highlight the Contribution of Astrocytic Tau. [PDF]

Neurosci Bull
Zhang R, Dong X, Pei G, Huang S.
europepmc   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Correction: Song et al. AXL Inactivation Inhibits Mesothelioma Growth and Migration via Regulation of p53 Expression. <i>Cancers</i> 2020, <i>12</i>, 2757. [PDF]

Cancers (Basel)
Song W, Wang H, Lu M, Ni X, Bahri N, Zhu S, Chen L, Wu Y, Qiu J, Fletcher JA, Ou WB.   +10 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Defining Human Differences in Biomedicine

An extensive literature reflects millennia of concern over what we humans call ourselves and others. All life sciences are now grappling further with how to categorize and study the nearly infinite polymorphisms within and among “species†as awareness
Maggie Brown
core  

Structural insights into Mitoguardin-1-mediated mitochondrial contact surfaces in fusion and lipid binding. [PDF]

Cell Discov
Yang K, Deng J, Yu F, Wang L, Yuan X, Ruan K, Yao X, Shi Y, Zhang L.   +8 more
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Development of mitochondrial mutator pigs exhibiting increased mitochondrial DNA mutations and premature aging via prime editing. [PDF]

Sci Adv
Chen F, Liang Y, Zheng W, Yao A, Wang N, Chen H, Zhuang Z, Lian M, Zhao Y, Ouyang Z, Zhou Z, Ge W, Liu Q, Ye Y, Lai L, Wang K.   +15 more
europepmc   +1 more source