Results 71 to 80 of about 39,862 (302)

Patterns and determinants of breastfeeding and complementary feeding practices in urban informal settlements, Nairobi Kenya

, 2011
BackgroundThe World Health Organisation (WHO) recommends exclusive breastfeeding during the first six months of life for optimal growth, development and health.
Kyobutungi, Catherine, Catherine Kyobutungi, Gitau, Tabither, Madise Nyovani J, Kyobutungi Catherine, Jean-Christophe Fotso, Fotso Jean-Christophe, Madise, Nyovani J., Kimani-Murage Elizabeth W, Yatich Nelly, Elizabeth W Kimani-Murage, Tabither M Gitau, Mutua, Martin K., Kimani-Murage, Elizabeth, Nyovani J Madise, Nelly Yatich, Martin K Mutua, Yatich, Nelly, Gitau Tabither M, Fotso, Jean-Christophe, Mutua Martin K   +20 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Technology, Monopoly, and the Decline of the Viatical Settlements Industry [PDF]

The viatical settlement industry provides an opportunity for terminally-ill consumers, typically HIV patients, to exploit a previously untapped source of equity in existing life insurance contracts to finance consumption and medical expenses.
Neeraj Sood, Abby Alpert, Jay Bhattacharya   +2 more
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Why do some informal settlements fare better than others? A mixed-methods analysis of water and sanitation inequities across informal settlements

Environmental Research: Infrastructure and Sustainability
Over three hundred million people in South Asian cities live in informal settlements. The administrative and socio-economic contexts in which these informal settlements emerge exhibit significant heterogeneity, influencing their access to water and ...
Hassaan Furqan Khan
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

The politics of leadership organizing in informal settlements: ambiguities of speaking publicly and mediating conflicting institutional logics

, 2014
Includes bibliographical references.This thesis examines the politics of leadership organizing in three informal settlements in Cape Town. Building on the facts that internal informal settlement politics is tense and leadership organizing fragmented and ...
Drivdal, Laura Elisabet
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Rethinking the second life of post-disaster and post-conflict temporary housing

Buildings & Cities
Providing temporary housing (TH) units after natural hazards and social conflicts is often an urgent necessity. Beyond their initial configuration, the second life of these units is crucial, given their temporary nature.
Ni̇l Akdede, Beki̇r Özer Ay, İpek Gürsel Di̇no   +2 more
doaj   +1 more source

Karnak: Settlements [PDF]

, 2011
At Karnak, in addition to the well known temples, there is another type of architecture: the settlements. They are a testimony of the everyday life of the ancient Egyptians for which remains have been found throughout all of the temples of Karnak ...
Masson, Aurélia, Millet, Marie
core