Results 91 to 100 of about 17,240,228 (299)

Effects of Advanced Trauma Life Support® training compared with standard care on adult trauma patient outcomes (ADVANCE TRAUMA): study protocol for a stepped-wedge cluster randomised trial

Trials
Background Advanced Trauma Life Support® (ATLS®) is the most widely adopted form of trauma life support training worldwide, but there is no high-quality evidence that it can improve patient outcomes.
Samriddhi Ranjan, Sara Fälth, Prashant Kharat, Abhinav Bassi, Girish D. Bakhshi, Debojit Basak, Johanna Berg, Shamita Chatterjee, Li Felländer-Tsai, Karla Hemming, Vivekanand Jha, Jessica Kasza, Monty Khajanchi, James Martin, Anurag Mishra, Anna Olofsson, Nobhojit Roy, Rajdeep Singh, Kapil Dev Soni, Martin Gerdin Wärnberg   +19 more
doaj   +1 more source

Extracorporeal membrane oxygenation for life-threatening asthma refractory to mechanical ventilation: analysis of the Extracorporeal Life Support Organization registry

Critical Care, 2017
Background The use of extracorporeal membrane oxygenation (ECMO) in cases of near-fatal asthma (NFA) has increased, but the benefits and potential complications of this therapy have yet to be fully investigated.
Hye Ju Yeo, Dohyung Kim, Doosoo Jeon, Yun Seong Kim, Peter Rycus, Woo Hyun Cho   +5 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Evidence-based planning and costing palliative care services for children : novel multi-method epidemiological and economic exemplar [PDF]

, 2013
Background: Children’s palliative care is a relatively new clinical specialty. Its nature is multi-dimensional and its delivery necessarily multi-professional.
Lucie Hobson, Virginia Bennett, Mary Devins, Hastings, R.P., Devins, Mary, Ciarán Humphreys, Edwards, Rhiannon Tudor, Spencer, Llinos Haf, Jane Noyes, Totsika, V., Humphreys, Ciarán, Hastings, Richard P., Rhiannon Tudor Edwards, Mary Lewis, Devins, M., Hain, Richard, Lewis, M., Totsika, Vasiliki, Hobson, Lucie, Lewis, Mary, Llinos Haf Spencer, Davies, G.R., Spencer, L.H., Richard Hain, Hobson, L., Noyes, J., Hain, R., Davies, Gareth R., Edwards, R.T., Humphreys, C., Hastings, Richard P.; id_orcid, Noyes, Jane, Richard P Hastings, Bennett, Virginia, Vasiliki Totsika, Bennett, V., Gareth R Davies   +36 more
core   +2 more sources

Allergy-associated acute coronary syndrome without anaphylaxis in a prospective observational study

Scientific Reports
Kounis syndrome is an acute coronary syndrome (ACS) triggered by allergic reactions via mast cell activation, classically accompanied by anaphylaxis. However, ACS associated with mild or subclinical allergic reactions may be underrecognized.
Mari Amino, Shie Takizawa, Seiji Morita, Kanae Kitatani, Ayumi Sasaki, Atsuhiko Yagishita, Yoshihide Nakagawa, Yuji Ikari, Koichiro Yoshioka   +8 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

The experiences and expectations of care and support among older migrants in the UK [PDF]

, 2012
This paper reports and critically discusses, against the literature on culturally sensitive and cultural competency practices, the findings of a qualitative study which explored the needs and expectations of older people and their carers from eight ...
Giuntoli, Gianfranco, Cattan, Mima, Giuntoli, G, Cattan, M, Mima Cattan, Gianfranco Giuntoli   +5 more
core   +1 more source

No evidence for a causal link between Helicobacter pylori infection and Irritable bowel syndrome: a Mendelian randomization study

Frontiers in Microbiology
BackgroundAlthough clinical studies have revealed a potential link between Helicobacter pylori (H. pylori) infection and irritable bowel syndrome (IBS), the causal relationship between them remains unknown.
Chenchen Wang, Chenchen Wang, Jing Zhang, Fengli Han, Dong Liu, Yuying Han   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Cancer patients' care at the end of life in a critical care environment: perspectives of families, patients and practitioners [PDF]

Innovations in cancer care requiring intensive support, and improved cancer patient survival in and out of critical care, have led to greater numbers of cancer patients than ever accessing critical care.
Pattison, Natalie
core