Results 101 to 110 of about 6,730,594 (397)

A prospective feasibility study evaluating the implementation of model-informed precision dosing in critically ill children

Frontiers in Pharmacology
Achieving optimal antibiotic exposure in critically ill pediatric patients is difficult due to (their) dynamic physiology and variability. Conventional weight-based regimens often fail to reach pharmacokinetic/pharmacodynamic (PK/PD) targets for narrow ...
Izgi Bayraktar, Merve Kaşıkcı, Zuhal Benek, Karel Allegaert, Karel Allegaert, Karel Allegaert, Karel Allegaert, Berna Egehan Oruncu, Selman Kesici, Benan Bayrakci, Nadir Yalcin   +10 more
doaj   +1 more source

Physiological and Technical Considerations of Extracorporeal CO2 Removal

Critical Care, 2019
This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2019. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2019.
Christian Karagiannidis, Felix Hesselmann, Eddy Fan   +2 more
doaj   +1 more source

Impact of palliative home care support on the quality and costs of care at the end of life: a population-level matched cohort study

BMJ Open, 2019
Objectives To evaluate the impact of palliative home care support on the quality of care and costs in the last 14 days of life. Design Matched cohort study using linked administrative databases. Setting All people who died in Belgium in 2012 (n=107 847).
Arno Maetens, K. Beernaert, Robrecht De Schreye, K. Faes, L. Annemans, K. Pardon, L. Deliens, Joachim Cohen   +7 more
semanticscholar   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Extracorporeal membrane oxygenation for life-threatening asthma refractory to mechanical ventilation: analysis of the Extracorporeal Life Support Organization registry

Critical Care, 2017
Background The use of extracorporeal membrane oxygenation (ECMO) in cases of near-fatal asthma (NFA) has increased, but the benefits and potential complications of this therapy have yet to be fully investigated.
Hye Ju Yeo, Dohyung Kim, Doosoo Jeon, Yun Seong Kim, Peter Rycus, Woo Hyun Cho   +5 more
doaj   +1 more source

How much ambulance personnel know about basic life support (BLS)? A hospital-based study from Eastern India

Journal of Family Medicine and Primary Care, 2020
Background: Basic life support (BLS) is an important component of emergency medical management. Ambulance personnel play a key role in resuscitation to save a life before reaching the hospital.
Upendra Hansda, Sangeeta Sahoo, Sankalan Biswas, Chitta Ranjan Mohanty, Sadananda Barik, Prajna Paramita Giri   +5 more
doaj   +1 more source

The Extracorporeal Life Support Organization Maastricht Treaty for Nomenclature in Extracorporeal Life Support. A Position Paper of the Extracorporeal Life Support Organization

American Journal of Respiratory and Critical Care Medicine, 2018
&NA; Extracorporeal life support (ECLS) was developed more than 50 years ago, initially with venoarterial and subsequently with venovenous configurations.
S. Conrad, M. Broman, F. Taccone, R. Lorusso, M. Malfertheiner, F. Pappalardo, M. Nardo, M. Belliato, L. Grazioli, R. Barbaro, M. McMullan, V. Pellegrino, D. Brodie, M. Bembea, E. Fan, M. Mendonca, R. Diaz, R. Bartlett   +17 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Psoriasis today: experiences of healthcare and impact on quality of life in a major UK cohort [PDF]

, 2015
Aim: To establish how people with psoriasis in the United Kingdom today experience living with their condition including diagnosis, treatment, healthcare provision and impact on daily life.
Gilbert, Annie, McAteer, Helen, Nash, Avril, Penzer, Rebecca, Schofield, Julia   +4 more
core   +1 more source

The adaptation of the therapeutic effort: science, technology and society

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2018
The scientific and technological development has an impact in all the spheres of society. The adaptation of the therapeutic effort is example of this. The author’s motive to carry out this bibliographic review article laid on the technological abuse as a
Gilberto de Jesús Betancourt-Betancourt, Gilberto Lázaro Betancourt-Reyes, Nguyen Castro-Gutierrez   +2 more
doaj